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Pre-implantation-diagnostics (PID / PGD)

Pre-Implantation-Diagnostics (PID) or Pre-Implantation-Genetic-Diagnosis (PGD) as it is known in Anglo-American countries has originally been developed as an alternative to prenatal diagnosis. Prenatal diagnosis involves performing amniocentesis or chorionic biopsy.

Pre-implantation-diagnostic testing allows the identification of possible chromosomal and genetic defects thus preventing affected egg cells from being transferred to the uterus.

Using the so called blastomere-biopsy (8-cell stage), diseased cells may be identified thus preventing affected embryos to be transferred to the uterus.

This is relevant, since 70 % of all miscarriages are linked to genetic disorders.

Prenatal diagnosis is only possible when a pregnancy is already established, whereas PID/PGD can be performed on the embryo before pregnancy occurs.

The PID technique involves investigating the genetic material of a single cell for possible defects. This can either be done by using the Polymerase Chain Reaction (PCR) or the Fluorescence In Situ Hybridisation (FISH) method.

 

Pilsen


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IVF Centers Prof. Zech
Austria
Bregenz
Tel.: +43 5574 44836
zech@ivf.at
Austria
Salzburg
Tel.: +43 662 9010 5000
office@kinderwunsch-salzburg.at
Switzerland
Niederuzwil
Tel.: +41 71 950 1580
zech@fivet-ivf.ch
Liechtenstein
Vaduz
Tel.: +423 237 6655
zech@ivf.li
Czech Republic
Pilsen
Tel.: +42 0377 279 350
zech@ivf-institut.cz
Italy
Meran
Tel.: +39 0473 270470
zech@fivet-ivf.it

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